Follistatin 344; Follistatin 315

85% Human Growth Peptides Follistatin 344 Follistatin 315 Raw Powder

Follistatin 344 Peptide Profile: 

Name:Follistatin 315 antibody
Physical State: Lyophilized Powder

Follistatin 344 Synonyms: FST344 , FS, Activin-binding protein.

Follistatin 344 Appearance: Sterile Filtered White Lyophilized (Freeze-Dried)

Follistatin 344 Manufacturer: Huao

Follistatin 344 Purity (by HPLC): 99.00%

Follistatin 344 Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.

Volume Before Lyophilized:500ul

Concentration(mg/ml):1.0mg/ml

Purity:85% by SDS-PAGE

Packing: 1mg / vial

Follistatin 344 Peptide Specification:

Follistatin 344 Description:

Follistatin 344 FST is a single chain gonadal protein that specifically inhibits follicle stimulating hormone release. The single FST gene encodes two isoforms Follistatin 317 and Follistatin 344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. 

In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.

Follistatin 344 Benefits
1) Follistatin 344 / FST works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth

2) Follistatin 344 / FST promote muscle growth due to the unique mechanism of action, FST joint use of steroids, IGF has better results. It only acts on muscle tissue, after use will not cause the proliferation of other tissue cells.

Follistatin 344 Application:

Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.

Follistatin works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth.

In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH).
High FSH levels in men may indicate that testicles are not functioning correctly; This condition limits muscle growth, recovery, and normal hormonal function. However, FSH levels that are too low can also negatively impact health and reproductive capabilities.

Follistatin 344 used for Muscle Growth:

Follistatin works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth. It’s also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow.

In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function. However, FSH levels that are too low can also negatively impact health and reproductive capabilities.

Administering FS344 via a small virus (re: adeno-associated virus/AAV) can increase muscle size and strength in animal species ranging from mice to monkeys with no significant adverse effects on organs, reproductive capabilities, serum estradiol (re: primary female sex hormone), luteinizing hormone (LH), and FSH levels. When scientists administered follistatin in mice with spinal muscular atrophy, the mice experienced increased muscle mass, improved motor function, and a 30% longer lifespan compared to mice in the control group.